1. NAME OF COURSE  / MODULE  MICROBIOLOGY
2. COURSE CODE PAV3016
3. NAME(S) OF ACADEMIC STAFF Dr Nurul Azmawati Mohamed (Coordinator)

Professor Datin Dr Che Ilina Isahak

Dr. Parikial George Joseph

Dr Wan Shahida Wan Sulaiman

4. RATIONALE FOR THE INCLUSION OF THE COURSE/MODULE IN THE PROGRAMME Basic Medical Science Course
5. SEMESTER & YEAR OFFERED Semester 1 & 2 in Year 3
6. TOTAL STUDENT LEARNING TIME (SLT) Face to face:

L T P O
52 26 39 16

L=lecture ; T=Tutorial; P=Practical; O=Others (Exam)

Total Guided and Independent Learning:

133+116=249
7. CREDIT VALUE 249/40= 6.2( 6 credit)
8. PREREQUISITE (IF ANY) Nil
9. OBJECTIVES By the end of the course, the students are expected to :

  1. Describe the basic concepts and principles of Microbiology and Immunology and their relation to understanding of infectious diseases.
  2. Describe the aetiological agents of infectious diseases.
  3. Describe and perform common laboratory procedures employed in diagnosing  infective diseases.
  4. Apply the  basic principles of epidemiology, treatment, prevention and control of infectious diseases and immunological conditions.
10. LEARNING OUTCOMES Upon successful completion of this course students should be able to:

  1. Relate the immune response to microbial invasion and other immunological conditions (LO1,C3)
  2. Relate the pathogenesis of infectious disease to clinical presentation and infection control (LO1,C3)
  3. Perform selected laboratory diagnostic procedures to identify microorganisms  causing the diseases (LO2,P3)
  4. Outline the treatment and prevention  of  common microbiological diseases  in accordance with accepted principles of  evidence-based practice (LO3-CTPS, A3)
11. TRANSFERABLE SKILLS
  • Deducting causal relationship between infections and diseases.
  • Performing and Interpreting   common microbiology laboratory procedures.
  • Effective communication through discussion during lectures, practicals, tutorials, seminar and PBL.
  • Critical thinking and problem solving in rationalizing how best to treat and prevent infectious diseases.
12. TEACHING-LEARNING AND ASSESSMENT STRATEGY Teaching-learning strategy:

Interactive sessions via lectures and tutorials.

Hands-on sessions via practical.

Directed-self learning via PBL and seminars.

 Assessment strategy:

  • Formative  (tutorials and PBL)
  • Summative assessment
13. SYNOPSIS Microbiology covers immunology, bacteriology, virology, and mycology. Students are required to grasp the immunological concepts of the body’s defence system in dealing with pathogens, the general and specific characteristics of micro-organisms, their pathogenicity, methods employed in identification of pathogens or the diagnosis of infectious and autoimmune diseases, control of micro-organisms and potential research areas. Various teaching-learning methods comprising of lectures, interactive tutorials, practical sessions, and mini PBL would be used to ensure that learning medical microbiology is made easy to comprehend and  effective.
14. MODE OF DELIVERY Lecture, Tutorial, Practical, Seminar, Problem-Based Learning.
15. Assessment methods and types
Summative Assessment (100%)
Category Percentage Percentage (Total of final) Assessment method
End Semester 1 Examination 75% 30% MCQ, MEQ, OSPE
Mid Semester 2 Examination 25% MCQ
Second Professional Examination. 100% 70% MCQ, MEQ, OSPE
16. MAPPING OF THE COURSE/MODULE TO THE PROGRAMME AIMS Rujuk Lampiran A
17 MAPPING OF THE COURSE/MODULE TO THE PROGRAMME LEARNING OUTCOMES Rujuk Lampiran B
18. Content outline of the course/module and SLT per topic
Topics FACE TO FACE SELF-STUDY TOTAL SLT
Lecture Tutorial Practical SLP Library search Self-study
Input 1: Introduction To Microbiology Course & Microbiology Laboratory

  1. Introduction to microbiology
  2. Sterilisation & disinfection (SLP)
1 2 3 1 2 9
Input 2: Immunology

  1. Overview and organization of the immune system
  2. Antigen recognition & HLA
  3. Antibody and T cell receptor
  4. Innate immunity
  5. Antigen-antibody reactions
  6. Immune response
  7. Hypersensitivity
  8. Autoimmunity &Tolerance
  9. Immunodeficiency
  10. Tumour immunology & Transplantation
  11. Immunisation
11 4 6 13 34
Input 3 : Bacteriology

  1. The bacterial cell
  2. Bacterial genetics
  3. Bacterial growth and nutrition
  4. Bacterial pathogenicity
  5. Overview of lab diagnosis of bacterial infection (SLP)
  6. Gram positive bacteria I
  7. Gram positive bacteria II
  8. Gram negative bacteria I
  9. Gram negative bacteria II
  10. Anaerobes
  11. Mycobacterium & Actinomycetes
  12. Rickettsia, Orientia, Coxiella, Ehrlichia, Bartonella
  13. Spirochaetes
  14. Chlamydia, Mycoplasma & Ureaplasma
  15. Antimicrobial drug
  16. Seminar
14 8 12 1 2 25 62
Input 4: Mycology

  1. Introduction to mycology
  2. Superficial mycosis
  3. Subcutaneous mycosis
  4. Systemic Mycoses and mycotoxicosis infections
  5. Procedures in Mycology (SLP)
4 2 3 1 5 15
Input 5 : Virology

  1. Introduction to virology
  2. General virology
  3. Pathogenesis of viral infections
  4. Immune response to viral infections
  5. Laboratory diagnosis of viral infections
 

5

 

2

 

3

 

 

 

 

 

6

 

16

Input 6 : Systemic Infections

  1. Infections of the respiratory tract I
  2. Infections of the respiratory tract II
  3. Infective endocarditis, bacteremia & sepsis
  4. Infections of the muscle, skin & appendage, bones & joints
  5. Infections of the urinary tract
  6. Infections of the gastrointestinal system
  7. Food-borne diseases
  8. Viral hepatitis
  9. Hepatobiliary infections
  10. Infections of the central nervous system
  11. Infections of the reproductive system I (bacteria)
  12. Infections of the reproductive system II (virus)
  13. Congenital infections
  14. Arboviruses and haemorrhagic fever viruses
  15. Introduction to zoonoses
  16. Normal flora & opportunistic infections
  17. Hospital acquired infection
  18. Rational Use of antibiotics (SLP)
17 8 12 1 35 73
Assessment and preparation 10 30 40
Total 52 26 49 4 2 116 249
19. References
  1. Lewinson W. 2012. Review of Medical Microbiology & Immunology. 12th Edition. McGraw  Hill.
  2. Abbas, A. K., Lichtman A. H. 2011. Basic Immunology: Functions and Disorders of   the Immune System. 3rd Edition Elsevier.
  3. Murray, P. R., Rosenthal, K. S., Pfaller, M. A. 2009. Medical Microbiology. 6th Edition. Philadelphia : Mosby/Elsevier.
  4. Ryan, K. J., Ray, C. G., Sherris, J. C. 2010. Sherris Medical Microbiology: an introduction to infectious diseases.  McGraw-Hill.
  5. Goering, R. V., Mims, C. A., 2013. Mims’ Medical Microbiology. C. A. 5th Edition.  PA: Mosby Elsevier.
  6. Todd, I, Spickett, G., Reeves, W. G. 2010. Lecture Notes on Immunology. 6th ed. Malden, Mass.: Blackwell Pub.
  7. Peakman, M & Vergani, D. 2009. Basic and Clinical Immunology. 2nd ed.. Churchill Livingstone.
  8. Brooks, G. F., Carroll, K. C., Butel, J. S., J. L., Morse, S. A. ,Mietzner T.A.2010. Jawetz, Melnick and Adelberg’s Medical Microbiology. 25th ed. McGraw-Hill.
  9. Greenwood, D.,Barer M., Slack R., Irving W. 2012. Medical Microbiology: a Guide to Microbial Infections: Pathogenesis, Immunity, Laboratory Diagnosis, and Control. 18th ed. Churchill Livingstone/ Elsevier.
20. OTHER ADDITIONAL INFORMATION nil

 

Lampiran A

Matrix of Course Learning Outcomes (CLO) vs Programme Educational Objectives (PEO)

Faculty :Faculty of Medicine and Health Sciences

Programme:Medical Programme

Course:Microbiology

Cource Code:PAV 3016

Course Learning Outcomes  Compliance to PEO Delivery  Assessment Key Performance Indicators/Index
PEO-1 PEO-2  PEO-3

PEO-4

1  

relate the immune response to microbial invasion and other immunological conditions (LO1,C3)

Lecture, Tutorial, Practical, Seminar, Self-Learning Package,

Problem base learning

Minitest Mid Semester /End Semester/ Professional Exam Students are able to relate the immune response in infectious diseases.

80% achieving grade C and above for final exam

2  

relate the pathogenesis of infectious disease to clinical presentation and infection control (LO1,C3)

Lecture, Tutorial, Practical, Seminar, Self-Learning Package,

Problem base learning

Minitest

Mid Semester /End Semester/ Professional Exam

Students are able to relateinfectious disease to clinical presentation and infection control.

80% achieving grade C and above for final exam

3  

perform selected laboratory diagnostic procedures to identify microorganisms  causing the diseases (LO2,P3)

Practical End Semester/ Professional Exam Students are able to interpret the routine microbiological laboratory tests

80% achieving grade C and above for final exam

4 explain treatment and prevention  of  common microbiological diseases  in accordance with accepted principles of  evidence-based practice (LO3-CTPS, A3) Lecture, Tutorial, Practical, Seminar, Self-Learning Package,

Problem base learning

Minitest

Mid Semester /End Semester/ Professional Exam

Students are able to suggest appropriate antimicrobial treatment and preventive measures.

80% achieving grade C and above for final exam

Total

4 4 3

 

Lampiran B

Matrix of Course Learning Outcomes (CLO) vs Programme Learning Outcomes (PLO)

Faculty : :Faculty of Medicine and Health Sciences

Programme:Medical Programme

Course: Microbiology

Course Code:PAV 3016

Course Learning Outcomes  Compliance to PLO Delivery Assessment  Key Performance Indicators/Index 
LO-1 LO-2 LO-3 LO-4 LO-5 LO-6 LO-7 LO-8

 LO-9

1  

relate the immune response to microbial invasion and other immunological conditions (LO1,C3)

/

 

C3

 

 

 

 

 

 

Lecture, Tutorial, Practical, Seminar, Self-Learning Package,

Problem base learning

Minitest

Mid Semester /End Semester/ Professional Exam

Students are able to relate the immune response in infectious diseases.

80% achieving grade C and above for final exam

2 relate the pathogenesis of infectious disease to clinical presentation and infection control (LO1,C3) /

C3

 

 

 

Lecture, Tutorial, Practical, Seminar, Self-Learning Package,

Problem base learning

Minitest

Mid Semester /End Semester/ Professional Exam

Students are able to relateinfectious disease to clinical presentation and infection control.

80% achieving grade C and above for final exam

3 perform selected laboratory diagnostic procedures to identify microorganisms  causing the diseases (LO2,P3)  

 

 

 

 

 

/

 

P3

 

 

 

 

 

 

 

 

 

 

Practical End Semester/ Professional Exam Students are able to interpret the routine microbiological laboratory tests

80% achieving grade C and above for final exam

4 explain treatment and prevention  of  common microbiological diseases  in accordance with accepted principles of  evidence-based practice (LO3-CTPS, A3)  

 

 

 

 

 

/

A3

CTPS

 

 

 

 

 

 

 

Lecture, Tutorial Minitest

Mid Semester /End Semester/ Professional Exam

Students are able to suggest appropriate antimicrobial treatment and preventive measures.

80% achieving grade C and above for final exam

Total  

2

 

1

 

1