1. NAME OF COURSE  / MODULE BIOCHEMISTRY I
2. COURSE CODE PAB1013
3. NAME(S) OF ACADEMIC STAFF
  1. Dr. Faizul Helmi Addnan (Coordinator)
  2. Prof. Dr. Nor Aripin Shamaan
  3. Dr. Nazefah Abdul Hamid
  4. Dr. Nur Fariha Mohd. Manzor
  5. Dr. Nuruliza Roslan
4. RATIONALE FOR THE INCLUSION OF THE COURSE/MODULE IN THE PROGRAMME Basic medical science course.
5. SEMESTER & YEAR OFFERED Semester 1/ Year 1
6. TOTAL STUDENT LEARNING TIME (SLT) Face to face:

L T P/S O
18 10 12 2.25

L=Lecture ;  S=Seminar;   O=Others (Exam)

Total Guided and Independent Learning:

42.25+(1+2+74.75) = 120

120
7. CREDIT VALUE 120/40= 3.0  (3 credit)
8. PREREQUISITE (IF ANY) Nil
9. OBJECTIVES The course objectives are:

1.     to discuss biochemical concepts in relation to medicine.

2.     to describe the structure and functions of biomolecules in the human body.

3.     to relate between chemistry and biological processes in the human body.

10. LEARNING OUTCOMES Upon completion of this course, students will be able to:

1.       explain the biochemical concepts used in medicine (LO1, C2)

2.       apply the biochemical concepts in relation to medicine (LO3,C3)

3.       relate biochemical concepts in the normal and diseased states (LO2, P2, A3)

11. TRANSFERABLE SKILLS
  • Conduct basic biochemical tests
  • Interpretation of basic biochemical examination results
  • Effective communication
  • Critical thinking and problem solving
12. TEACHING-LEARNING AND ASSESSMENT STRATEGY Teaching-learning strategy:

 The course will be taught through a combination of lectures, formal tutorial, exercise, group work, using authentic situational or problem solving materials and self directed learning packages. Collaborative teamwork will be fostered throughout the course. The use of in class individual and group presentation or discussion will assess the student’s ability to apply critical thinking and encourage students to respond and participate actively in class.

  • Interactive sessions
  • Hands-on sessions
  • Directed-self learning

 Assessment strategy:

Continuous assessment (mid semester and end semester examination).

13. SYNOPSIS This course is designed to help student understand key concepts and appreciate the significant connections between chemistry, health and the treatment of disease. The course covers concepts in organic, inorganic and biological chemistry, the balance between theoretical and practical chemistry while emphasizing molecules unique to health, understanding the relationship between structure and functions of the major biomolecules of clinical significance in the human body.
14. MODE OF DELIVERY Lecture, Tutorial, Practical, Seminar, Self-learning package, Self-directed learning.
15. Assessment methods and types
Summative  Assessment (100%)
Category Percentage Assessment method
Continuous assessment 30% MCQ
End Semester  Examination 70% MCQ, MEQ
16. MAPPING OF THE COURSE/MODULE TO THE PROGRAMME AIMS Rujuk Lampiran A
17. MAPPING OF THE COURSE/MODULE TO THE PROGRAMME LEARNING OUTCOMES Rujuk Lampiran B
18. Content outline of the course/module and SLT per topic
Topics FACE TO FACE SELF-STUDY TOTAL SLT
Lecture Tutorial Assessment/Practical Seminar SLP SDL Self-study
INPUT 1: PHYSICOCHEMICAL AND BIOLOGICAL FOUNDATION OF BIOCHEMISTRY

  • L1: Introduction to Biochemistry
  • P1: Introduction to Laboratory Equipments
  • L2: pH, acid, base, buffer(NAS)
  • SDL1: Expression of Concentration
  • L3: Absorption, Elution and Colloids
  • P2: Spectrophotometry
  • L4: Types of Isomerism
  • L5: Chemical properties of enzymes
  • L6: Enzymes Classification, Kinetics & Specificity
  • L7: Regulation of Enzyme Activities
  • P3: Factors affecting enzyme activities (NR)
  • P4: Enzyme kinetics (FHA/NAS)

·         L8: Vitamins (FHA)

·         L9: Minerals (FHA)

·         SLP1: Minerals (SLP: FHA)

·         L10: Coenzymes (NR)

·         L11: Enzyme in Medicine (NR)

·         SDL2: Enzymes (NR)

11 6 12 1 2 22+12+12=46 78
INPUT 2: BLOOD AND BODY FLUIDS

·         L1: CSF, Urine and Other Fluids

·         L2: Blood Components and Plasma Proteins

·         L3: Hemoglobin Synthesis and Degradation

3 2 6+4=10 15
INPUT 3:    BIOENERGETICS

·         L1: Energy Rich Compounds (NAS)

·         L2: Gibbs Free Energy (NAS)

·         L3: Thermodynamics I

·         L4: Thermodynamics II

 

4

 

2 8+4= 12 18
Assessment (others) 2.25 6.75 9
Total 18 10 14.25 1 2 74.75 120
19.
  • MAIN References SUPPORTING THE COURSE
  • ADDITIONAL REFERENCES SUPPORTING THE COURSE
1.           Liebermanns M and Marks AD. Mark’s Basic Medical Biochemistry: A Clinical Approach, 4th Edition. Lippincotts, Williams and Wilkins Publication. Wolters Kluwer Business. 2013

2.           Devlin, T. Textbook of Biochemistry with Clinical Correlations, 7th Edition. John Wiley & Sons, Inc. 2010.

3.           Nelsen  L., Cox MM. Lehnigher Principles of Biochemistry, 6th Edition, W.H Freeman. 2012

4.           Baynes JW and Dominiczak MH. Medical Biochemistry. 3rd edition. Mosby Elsevier Ltd. 2009.

5.           Murray R, Bender D, Botham KM, Kennelly PJ, Rodwell V and Weil PA.  Harper’s Illustrated Biochemistry. 28th Edition (Lange Basic Science). McGraw-Hill Publication. 2009.

20. OTHER ADDITIONAL INFORMATION  Nil

 

Lampiran A

 

Matrix of Course Learning Outcomes (CLO) vs Programme Educational Objectives (PEO)

Faculty : Faculty of Medicine and Health Sciences

Programme: MBBS

Course: Biochemistry I

Course Code: PAB1013

Course Learning Outcomes  Compliance to PEO Delivery  Assessment Key Performance Indicators/Index

 

PEO-1 PEO-2  PEO-3

PEO-4

1 To explain the biochemical concepts used in medicine. / Lecture, Tutorial, Practical, Seminar,

Self-learning package,

Self-directed learning.

Quiz

Mid Semester /End Semester/ Professional Exam

1. Students are able to describe and explain the concepts.

2. 80% should pass End Semester Examination.

2 To apply the biochemical concepts in relation to medicine. / Practical report

First Professional Exam (OSPE)

1. Students are able to explain biochemical concepts in relation to medicine.

2. 80% should pass End Semester Examination.

3 To relate biochemical concepts in the normal and diseased states. / / Quiz

Mid Semester /End Semester/ Professional Exam

1. Students are able to relate biochemical concepts in the normal and diseased states.

2. 80% should pass End Semester Examination.

Total

 2  1    1

 

Lampiran B

 

Matrix of Course Learning Outcomes (CLO) vs Programme Learning Outcomes (PLO)

 

Faculty : Faculty of Medicine and Health Sciences

Programme: MBBS

Course: Biochemistry I

Course Code: PAB 1013

 

Course Learning Outcomes  Compliance to PLO Delivery Assessment Key Performance Indicators/Index
LO-1 LO-2 LO-3 LO-4 LO-5 LO-6 LO-7 LO-8

 LO-9

1 To explain the biochemical concepts used in medicine (LO1 A3) /  

 

 

 

Lecture, Tutorial, Practical, Seminar,

Self-learning package,

Self-directed learning

Quiz

Mid Semester /End Semester/ Professional Exam

1. Students are able to describe and explain the concepts.

2. 80% should pass End Semester Examination.

2 To apply the biochemical concepts in relation to medicine (LO3 C3)  

 

/  

 

 

 

Practical report

First Professional Exam (OSPE)

1. Students are able to explain biochemical concepts in relation to medicine.

2. 80% should pass End Semester Examination.

3 To relate biochemical concepts in the normal and diseased states (LO2 P2) / Quiz

Mid Semester /End Semester/ Professional Exam

1. Students are able to relate biochemical concepts in the normal and diseased states.

2. 80% should pass End Semester Examination.

Total 1 1 1